Comparative cardiac effects of antimalarial drug halofantrine with or without concomitant administration of kolanut or fluconazole in healthy volunteers.

Adedapo, Aduragbenro DA; Ojji, Dike B; Adedapo, Kayode S; Kolade, Yetunde; Babalola, Chinedum P

Adedapo, Aduragbenro DA; Ojji, Dike B; Adedapo, Kayode S; Kolade, Yetunde; Babalola, Chinedum P.

Afiliação

Adedapo AD; Department of Pharmacology and Therapeutics, University of Ibadan, Nigeria.
Ojji DB; Department of Clinical Pharmacology, University College Hospital, Ibadan, Oyo State, Nigeria.
Adedapo KS; Cardiology Unit, Medicine Department, Gwagwalada Hospital, Abuja, Nigeria.
Kolade Y; Department of Chemical Pathology, University of Ibadan, Ibadan, Nigeria.
Babalola CP; Department of Pharmaceutical Chemistry, University of Ibadan, Ibadan, Nigeria.

Afr Health Sci ; 23(1): 262-269, 2023 Mar.

Article em En | MEDLINE | ID: mdl-37545974

Assuntos

Antimaláricos; Humanos; Antimaláricos/efeitos adversos; Estudos Cross-Over; Eletrocardiografia; Fluconazol/efeitos adversos; Voluntários Saudáveis

Palavras-chave

Drug interaction; QT prolongation; fluconazole; halofantrine; kolanut; malaria

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antimaláricos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antimaláricos Idioma: En Ano de publicação: 2023 Tipo de documento: Article