The anti-oncogenic effect of 17-DMAG via the inactivation of HSP90 and MET pathway in osteosarcoma cells.

Kawano, Masanori; Tanaka, Kazuhiro; Itonaga, Ichiro; Iwasaki, Tatsuya; Kubota, Yuta; Tsumura, Hiroshi

Kawano, Masanori; Tanaka, Kazuhiro; Itonaga, Ichiro; Iwasaki, Tatsuya; Kubota, Yuta; Tsumura, Hiroshi.

Afiliação

Kawano M; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, 879-5593, Japan.
Tanaka K; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, 879-5593, Japan.
Itonaga I; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, 879-5593, Japan.
Iwasaki T; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, 879-5593, Japan.
Kubota Y; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, 879-5593, Japan.
Tsumura H; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, 879-5593, Japan.

Oncol Res ; 31(5): 631-643, 2023.

Article em En | MEDLINE | ID: mdl-37547755

Assuntos

Antineoplásicos; Neoplasias Ósseas; Osteossarcoma; Humanos; Animais; Camundongos; Benzoquinonas/farmacologia; Antineoplásicos/farmacologia; Proliferação de Células; Apoptose; Osteossarcoma/tratamento farmacológico; Osteossarcoma/genética; Linhagem Celular Tumoral; Neoplasias Ósseas/tratamento farmacológico; Neoplasias Ósseas/genética; Proteínas de Choque Térmico HSP90

Palavras-chave

17-DMAG; HSP90; MET; Osteosarcoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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