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Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure.
Kato, Terukazu; Fukao, Keita; Ohara, Takafumi; Naya, Noriyuki; Tokuyama, Ryukou; Muto, Susumu; Fukasawa, Hiroshi; Itai, Akiko; Matsumura, Ken-Ichi.
Afiliação
  • Kato T; Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan.
  • Fukao K; Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan.
  • Ohara T; Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan.
  • Naya N; Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan.
  • Tokuyama R; Institute of Medicinal Molecular Design, Inc., Tokyo 113-0033, Japan.
  • Muto S; Institute of Medicinal Molecular Design, Inc., Tokyo 113-0033, Japan.
  • Fukasawa H; Institute of Medicinal Molecular Design, Inc., Tokyo 113-0033, Japan.
  • Itai A; Institute of Medicinal Molecular Design, Inc., Tokyo 113-0033, Japan.
  • Matsumura KI; Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan.
J Med Chem ; 66(16): 11428-11446, 2023 08 24.
Article em En | MEDLINE | ID: mdl-37552807
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR delta / Aterosclerose Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR delta / Aterosclerose Idioma: En Ano de publicação: 2023 Tipo de documento: Article