The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of <i>ST8SIA1</i>.

Pilgrim, Adeiye A; Jonus, Hunter C; Ho, Andrew; Cole, Anna C; Shim, Jenny; Goldsmith, Kelly C

The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1.

Pilgrim, Adeiye A; Jonus, Hunter C; Ho, Andrew; Cole, Anna C; Shim, Jenny; Goldsmith, Kelly C.

Afiliação

Pilgrim AA; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Jonus HC; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Ho A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Cole AC; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, GA, USA.
Shim J; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Goldsmith KC; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.

Oncoimmunology ; 12(1): 2240678, 2023.

Article em En | MEDLINE | ID: mdl-37554309

Assuntos

Neuroblastoma; Sialiltransferases; Proteínas de Sinalização YAP; Humanos; Regulação para Baixo; Proteínas de Homeodomínio/metabolismo; Proteínas de Homeodomínio/uso terapêutico; Imunoterapia/métodos; Neuroblastoma/tratamento farmacológico; Neuroblastoma/metabolismo; Animais; Sialiltransferases/metabolismo

Palavras-chave

GD2; YAP; chemoimmunotherapy; dinutuximab; neuroblastoma; relapse

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sialiltransferases / Proteínas de Sinalização YAP / Neuroblastoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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