Broad spectrum integrin inhibitor GLPG-0187 bypasses immune evasion in colorectal cancer by TGF-ß signaling mediated downregulation of PD-L1.

MacDonald, William J; Verschleiser, Brooke; Carlsen, Lindsey; Huntington, Kelsey E; Zhou, Lanlan; El-Deiry, Wafik S.

Afiliação

MacDonald WJ; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, The Warren Alpert Medical School, Brown University Providence, RI 02903, USA.
Verschleiser B; Legorreta Cancer Center at Brown University, The Warren Alpert Medical School, Brown University Providence, RI 02903, USA.
Carlsen L; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, The Warren Alpert Medical School, Brown University Providence, RI 02903, USA.
Huntington KE; Legorreta Cancer Center at Brown University, The Warren Alpert Medical School, Brown University Providence, RI 02903, USA.
Zhou L; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, The Warren Alpert Medical School, Brown University Providence, RI 02903, USA.
El-Deiry WS; Pathobiology Graduate Program, The Warren Alpert Medical School, Brown University Providence, RI 02903, USA.

Am J Cancer Res ; 13(7): 2938-2947, 2023.

Article em En | MEDLINE | ID: mdl-37559982