Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions.

The, Erlinda; Zhai, Yufeng; Yao, Qingzhou; Ao, Lihua; Li, Suzhao; Fullerton, David A; Dinarello, Charles A; Meng, Xianzhong

The, Erlinda; Zhai, Yufeng; Yao, Qingzhou; Ao, Lihua; Li, Suzhao; Fullerton, David A; Dinarello, Charles A; Meng, Xianzhong.

Afiliação

The E; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Zhai Y; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Yao Q; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Ao L; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Li S; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Fullerton DA; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Dinarello CA; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.
Meng X; Departments of Surgery and Medicine, University of Colorado Denver, Aurora, CO 80045.

Int J Biol Sci ; 19(12): 3908-3919, 2023.

Article em En | MEDLINE | ID: mdl-37564205

Assuntos

Estenose da Valva Aórtica; Valva Aórtica; Interleucina-1; Animais; Humanos; Camundongos; Anti-Inflamatórios; Estenose da Valva Aórtica/metabolismo; Células Cultivadas; Transdução de Sinais; Interleucina-1/farmacologia; Proteínas Recombinantes/farmacologia

Palavras-chave

IL-37; aortic valve; endocytic pathway; inflammation; nuclear action

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Valva Aórtica / Estenose da Valva Aórtica / Interleucina-1 Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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