Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data.

Chen, Siyi; Lin, Zhaotong; Shen, Xiaotong; Li, Ling; Pan, Wei

Chen, Siyi; Lin, Zhaotong; Shen, Xiaotong; Li, Ling; Pan, Wei.

Afiliação

Chen S; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Lin Z; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Shen X; School of Statistics, University of Minnesota, Minneapolis, Minnesota, USA.
Li L; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA.
Pan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.

Genet Epidemiol ; 47(8): 585-599, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37573486

Assuntos

Doença de Alzheimer; Estudo de Associação Genômica Ampla; Humanos; Estudo de Associação Genômica Ampla/métodos; Modelos Genéticos; Fenótipo; Doença de Alzheimer/genética

Palavras-chave

Alzheimer's disease; metabolomics; stepwise selection; structural equation modeling; two-stage least squares

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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