Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment.

Brockmueller, Aranka; Buhrmann, Constanze; Shayan, Parviz; Shakibaei, Mehdi

Brockmueller, Aranka; Buhrmann, Constanze; Shayan, Parviz; Shakibaei, Mehdi.

Afiliação

Brockmueller A; Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.
Buhrmann C; Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Shayan P; Department of Parasitology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Shakibaei M; Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.

Front Immunol ; 14: 1225530, 2023.

Article em En | MEDLINE | ID: mdl-37575245

Assuntos

Neoplasias Colorretais; Resveratrol; Sirtuína 1; Microambiente Tumoral; Proteína Supressora de Tumor p53; Apoptose; Resveratrol/farmacologia; Transdução de Sinais; Microambiente Tumoral/efeitos dos fármacos; Proteína Supressora de Tumor p53/efeitos dos fármacos; Proteína Supressora de Tumor p53/metabolismo; Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/metabolismo; Sirtuína 1/efeitos dos fármacos; Sirtuína 1/metabolismo

Palavras-chave

Sirt-1 modulation; apoptosis; caspase-3; colorectal cancer; p53; reciprocal crosstalk; resveratrol; tumor microenvironment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteína Supressora de Tumor p53 / Sirtuína 1 / Microambiente Tumoral / Resveratrol Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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