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Requirements for dose calculation on an active scanned proton beamline for small, shallow fields.
Knäusl, B; Langgartner, L; Stock, M; Janson, M; Furutani, K M; Beltran, C J; Georg, D; Resch, A F.
Afiliação
  • Knäusl B; Medical University of Vienna, Department of Radiation Oncology, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria. Electronic address: barbara.knaeusl@meduniwien.ac.at.
  • Langgartner L; Medical University of Vienna, Department of Radiation Oncology, Vienna, Austria.
  • Stock M; MedAustron Ion Therapy Center, Wiener Neustadt, Austria; Karl Landsteiner University of Health Sciences, Krems, Austria.
  • Janson M; RaySearch Laboratories, Stockholm, Sweden.
  • Furutani KM; Mayo Clinic, Department of Radiation Oncology, Jacksonville, FL, United States of America.
  • Beltran CJ; Mayo Clinic, Department of Radiation Oncology, Jacksonville, FL, United States of America.
  • Georg D; Medical University of Vienna, Department of Radiation Oncology, Vienna, Austria.
  • Resch AF; Medical University of Vienna, Department of Radiation Oncology, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Phys Med ; 113: 102659, 2023 Sep.
Article em En | MEDLINE | ID: mdl-37598612
ABSTRACT

INTRODUCTION:

A growing interest in using proton pencil beam scanning in combination with collimators for the treatment of small, shallow targets, such as ocular melanoma or pre-clinical research emerged recently. This study aims at demonstrating that the dose of a synchrotron-based PBS system with a dedicated small, shallow field nozzle can be accurately predicted by a commercial treatment planning system (TPS) following appropriate tuning of both, nozzle and TPS. MATERIALS A removable extension to the clinical nozzle was developed to modify the beam shape passively. Five circular apertures with diameters between 5 to 34mm, mounted 72cm downstream of a range shifter were used. For each collimator treatment plans with spread-out Bragg peaks (SOBP) with a modulation of 3 to 30mm were measured and calculated with GATE/Geant4 and the research TPS RayStation (RS11B-R). The dose grid, multiple coulomb scattering and block discretization resolution were varied to find the optimal balance between accuracy and performance.

RESULTS:

For SOBPs deeper than 10mm, the dose in the target agreed within 1% between RS11B-R, GATE/Geant4 and measurements for aperture diameters between 8 to 34mm, but deviated up to 5% for smaller apertures. A plastic taper was introduced reducing scatter contributions to the patient (from the pipe) and improving the dose calculation accuracy of the TPS to a 5% level in the entrance region for large apertures.

CONCLUSION:

The commercial TPS and GATE/Geant4 can accurately calculate the dose for shallow, small proton fields using a collimator and pencil beam scanning.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Oculares / Terapia com Prótons Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Oculares / Terapia com Prótons Idioma: En Ano de publicação: 2023 Tipo de documento: Article