Aquaporin 9 causes recurrent spontaneous abortion by inhibiting trophoblast cell epithelial-mesenchymal transformation and invasion through the PI3K/AKT pathway.

Ma, Nana; Liu, Bo; Jin, Yufu; Wang, Jiawei; Qin, Weili; Zheng, Fengque; Qin, Rongyan; Li, Jiaxu; Hang, Fu; Qin, Aiping

Aquaporin 9 causes recurrent spontaneous abortion by inhibiting trophoblast cell epithelial-mesenchymal transformation and invasion through the PI3K/AKT pathway.

Ma, Nana; Liu, Bo; Jin, Yufu; Wang, Jiawei; Qin, Weili; Zheng, Fengque; Qin, Rongyan; Li, Jiaxu; Hang, Fu; Qin, Aiping.

Afiliação

Ma N; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Liu B; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Jin Y; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Wang J; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Qin W; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Zheng F; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Qin R; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Li J; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Hang F; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.
Qin A; Center of Reproductive Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China.

Biol Reprod ; 109(5): 736-748, 2023 Nov 15.

Article em En | MEDLINE | ID: mdl-37602667

Assuntos

Aborto Espontâneo; Aquaporinas; Fragmentos de Peptídeos; Receptores do Fator de Crescimento Derivado de Plaquetas; Humanos; Gravidez; Feminino; Animais; Camundongos; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Trofoblastos/metabolismo; Aquaporinas/genética; Aquaporinas/metabolismo; Proliferação de Células; Transição Epitelial-Mesenquimal; Movimento Celular

Palavras-chave

AQP9; PI3K/AKT pathway; invasion; recurrent spontaneous abortion; trophoblast cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Aborto Espontâneo / Receptores do Fator de Crescimento Derivado de Plaquetas / Aquaporinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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