Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria. | Res Sq;2023 Aug 11. | MEDLINE

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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria.

Watson, Felicia N; Shears, Melanie J; Kalata, Anya C; Duncombe, Caroline J; Seilie, A Mariko; Chavtur, Chris; Conrad, Ethan; Talavera, Irene Cruz; Raappana, Andrew; Sather, D Noah; Chakravarty, Sumana; Sim, B Kim Lee; Hoffman, Stephen L; Tsuji, Moriya; Murphy, Sean C.

Afiliação

Watson FN; University of Washington.
Shears MJ; University of Washington.
Kalata AC; University of Washington.
Duncombe CJ; University of Washington.
Seilie AM; University of Washington.
Chavtur C; University of Washington.
Conrad E; University of Washington.
Talavera IC; University of Washington.
Raappana A; Seattle Children's Research Institute.
Sather DN; Seattle Children's Research Institute.
Chakravarty S; Sanaria Inc.
Sim BKL; Sanaria Inc.
Hoffman SL; Sanaria Inc.
Tsuji M; Columbia University.
Murphy SC; University of Washington.

Res Sq ; 2023 Aug 11.

Article em En | MEDLINE | ID: mdl-37609210

Palavras-chave

7DW8-5; CSP; Plasmodium; Trm cells; glycolipid adjuvant; intradermal; liver resident memory; prime-and-trap; sporozoites

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article