Light-activated microtubule-based two-dimensional active nematic.
Soft Matter
; 19(35): 6691-6699, 2023 Sep 13.
Article
em En
| MEDLINE
| ID: mdl-37609884
ABSTRACT
We assess the ability of two light responsive kinesin motor clusters to drive dynamics of microtubule-based active nematics opto-K401, a processive motor, and opto-K365, a non-processive motor. Measurements reveal an order of magnitude improvement in the contrast of nematic flow speeds between maximally- and minimally-illuminated states for opto-K365 motors when compared to opto-K401 construct. For opto-K365 nematics, we characterize both the steady-state flow and defect density as a function of applied light. We also examine the transient behavior as the system switches between steady-states upon changes in light intensities. Although nematic flows reach a steady state within tens of seconds, the defect density exhibits transient behavior for up to 10 minutes, showing a separation between small-scale active flows and system-scale structural states. Our work establishes an experimental platform that can exploit spatiotemporally-heterogeneous patterns of activity to generate targeted dynamical states.
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MEDLINE
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En
Ano de publicação:
2023
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Article