[Alcoholic hepatitis - current and future treatment approaches]. / Alkoholische Hepatitis Aktuelle und zukünftige Behandlungskonzepte.
Dtsch Med Wochenschr
; 148(17): 1095-1101, 2023 09.
Article
em De
| MEDLINE
| ID: mdl-37611573
ABSTRACT
Acute severe alcoholic hepatitis is a serious disease with poor prognosis. As a result of an improved understanding of the underlying pathomechanisms, a variety of new, innovative therapeutic modalities are currently being investigated that may help to improve prognosis. New approaches include the application of anti-inflammatory agents (e.g., interleukin-1 inhibitors), modifications of the gut-liver axis via fecal microbiome transfer or the administration of non-absorbable antibiotics (e.g., rifaximin), and drugs to enhance hepatocellular regeneration (e.g., interleukin-22 agonists). This article describes current management concepts of alcoholic hepatitis and provides an overview of new potential treatment approaches.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Microbiota
/
Hepatite Alcoólica
Idioma:
De
Ano de publicação:
2023
Tipo de documento:
Article