Re-routing GPR56 signalling using G&#945;<sub>12/13</sub> G protein chimeras.

Faas, Felix; Nørskov, Amalie; Holst, Peter J; Andersson, Anne-Marie; Qvortrup, Katrine; Mathiasen, Signe; Rosenkilde, Mette M

Re-routing GPR56 signalling using Gα_12/13 G protein chimeras.

Faas, Felix; Nørskov, Amalie; Holst, Peter J; Andersson, Anne-Marie; Qvortrup, Katrine; Mathiasen, Signe; Rosenkilde, Mette M.

Afiliação

Faas F; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nørskov A; Department of Chemistry, Technical University of Denmark, Lyngby, Denmark.
Holst PJ; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Andersson AM; InProTher APS, Copenhagen, Denmark.
Qvortrup K; InProTher APS, Copenhagen, Denmark.
Mathiasen S; Department of Chemistry, Technical University of Denmark, Lyngby, Denmark.
Rosenkilde MM; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

Basic Clin Pharmacol Toxicol ; 133(4): 378-389, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37621135

Assuntos

Receptores Acoplados a Proteínas G; Transdução de Sinais; Receptores Acoplados a Proteínas G/genética; Receptores Acoplados a Proteínas G/metabolismo; Proteínas de Ligação ao GTP/metabolismo; Peptídeos

Palavras-chave

G protein chimeras; G protein-coupled 7TM receptors; Type II: adhesion GPCRs; drug discovery and development; outcome measures

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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