The timing of transcription of RpoS-dependent genes varies across multiple stresses in Escherichia coli K-12.
mSystems
; 8(5): e0066323, 2023 Oct 26.
Article
em En
| MEDLINE
| ID: mdl-37623321
ABSTRACT
IMPORTANCE Bacteria adapt to changing environments by altering the transcription of their genes. Specific proteins can regulate these changes. This study explored how a single protein called RpoS controls how many genes change expression during adaptation to three stresses. We found that (i) RpoS is responsible for activating different genes in different stresses; (ii) that during a stress, the timing of gene activation depends on the what stress it is; and (iii) that how much RpoS a gene needs in order to be activated can predict when that gene will be activated during the stress of stationary phase.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas de Escherichia coli
/
Escherichia coli K12
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article