A focus on leucine in the nutritional regulation of human skeletal muscle metabolism in ageing, exercise and unloading states.

Ely, Isabel A; Phillips, Bethan E; Smith, Kenneth; Wilkinson, Daniel J; Piasecki, Mathew; Breen, Leigh; Larsen, Mads S; Atherton, Philip J

Ely, Isabel A; Phillips, Bethan E; Smith, Kenneth; Wilkinson, Daniel J; Piasecki, Mathew; Breen, Leigh; Larsen, Mads S; Atherton, Philip J.

Afiliação

Ely IA; Centre of Metabolism, Ageing & Physiology (COMAP), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research and Nottingham NIHR Biomedical Research Centre, Derby, DE22 3DT, UK.
Phillips BE; Centre of Metabolism, Ageing & Physiology (COMAP), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research and Nottingham NIHR Biomedical Research Centre, Derby, DE22 3DT, UK.
Smith K; Centre of Metabolism, Ageing & Physiology (COMAP), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research and Nottingham NIHR Biomedical Research Centre, Derby, DE22 3DT, UK.
Wilkinson DJ; Centre of Metabolism, Ageing & Physiology (COMAP), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research and Nottingham NIHR Biomedical Research Centre, Derby, DE22 3DT, UK.
Piasecki M; Centre of Metabolism, Ageing & Physiology (COMAP), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research and Nottingham NIHR Biomedical Research Centre, Derby, DE22 3DT, UK.
Breen L; School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Larsen MS; Arla Foods Ingredients Group P/S, Denmark.
Atherton PJ; Centre of Metabolism, Ageing & Physiology (COMAP), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research and Nottingham NIHR Biomedical Research Centre, Derby, DE22 3DT, UK. Electronic address: philip.atherton@nottingham.ac.uk.

Clin Nutr ; 42(10): 1849-1865, 2023 10.

Article em En | MEDLINE | ID: mdl-37625315

Assuntos

Proteínas Alimentares; Músculo Esquelético; Humanos; Leucina/metabolismo; Proteínas Alimentares/metabolismo; Músculo Esquelético/metabolismo; Aminoácidos Essenciais/metabolismo; Alvo Mecanístico do Complexo 1 de Rapamicina/metabolismo; Alvo Mecanístico do Complexo 1 de Rapamicina/farmacologia; Envelhecimento/metabolismo; Proteínas Musculares/metabolismo

Palavras-chave

Ageing; Exercise; Leucine; Muscle anabolism; Physical inactivity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Alimentares / Músculo Esquelético Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Alimentares / Músculo Esquelético Idioma: En Ano de publicação: 2023 Tipo de documento: Article