Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells.

Tsai, Feng-Lung; Huang, Han-Li; Lai, Mei-Jung; Liou, Jing-Ping; Pan, Shiow-Lin; Yang, Chia-Ron

Tsai, Feng-Lung; Huang, Han-Li; Lai, Mei-Jung; Liou, Jing-Ping; Pan, Shiow-Lin; Yang, Chia-Ron.

Afiliação

Tsai FL; School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Huang HL; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei 110, Taiwan.
Lai MJ; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Liou JP; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei 110, Taiwan.
Pan SL; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei 110, Taiwan.
Yang CR; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.

Int J Mol Sci ; 24(16)2023 Aug 09.

Article em En | MEDLINE | ID: mdl-37628767

Assuntos

Neoplasias Colorretais; Inibidores de Histona Desacetilases; Humanos; Inibidores de Histona Desacetilases/farmacologia; Apoptose; Proliferação de Células; Proteínas de Ciclo Celular; Histona Desacetilases; Células Endoteliais da Veia Umbilical Humana; Neoplasias Colorretais/tratamento farmacológico

Palavras-chave

HDAC inhibitors; apoptosis; cell cycle arrest; colorectal cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Inibidores de Histona Desacetilases Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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