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Daprodustat: A potential game-changer in renal anemia therapy-A perspective.
Haider, Muhammad Usman; Furqan, Muhammad; Mehmood, Qasim.
Afiliação
  • Haider MU; Department of Medicine, King Edward Medical University, Lahore, Punjab, Pakistan.
  • Furqan M; Department of Medicine, King Edward Medical University, Lahore, Punjab, Pakistan.
  • Mehmood Q; Department of Medicine, King Edward Medical University, Lahore, Punjab, Pakistan.
Front Pharmacol ; 14: 1249492, 2023.
Article em En | MEDLINE | ID: mdl-37637409
The United States FDA has approved daprodustat (DPD) as the first oral treatment option for anemia due to chronic kidney disease (CKD) in dialysis patients. Clinical trials have demonstrated DPD's efficacy and safety, showing non-inferiority to darbepoetin and suggesting reduced IV iron usage. DPD also holds potential for treating chronic kidney disease anemia in non-dialysis patients and may have benefits for patients with coexisting renal anemia and heart failure, pending further research and trials.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article