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Cerebrovascular Fibromuscular Dysplasia - A Practical Review.
Kesav, Praveen; Manesh Raj, Divya; John, Seby.
Afiliação
  • Kesav P; Department of Neurology, Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
  • Manesh Raj D; Research Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
  • John S; Department of Neurology and Neuro Interventional Surgery, Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Vasc Health Risk Manag ; 19: 543-556, 2023.
Article em En | MEDLINE | ID: mdl-37664168
Fibromuscular dysplasia (FMD) is a rare idiopathic, segmental, noninflammatory and nonatherosclerotic arteriopathy of medium-sized arteries. It is classically considered to be a disease of young and middle adulthood, with females more commonly affected than males. FMD is a systemic disease. Although historically considered to be rare, cerebrovascular FMD (C-FMD) has now been recognized to be as common as the renovascular counterpart. Extracranial carotid and vertebral arteries are the most commonly involved vascular territories in C-FMD with the clinical presentation determined by vessels affected. Common symptoms include headaches and pulsatile tinnitus, with transient ischemic attacks, ischemic stroke and subarachnoid or intracerebral hemorrhage constituting the more severe clinical manifestations. Cervical artery dissection involving carotids more often than vertebral arteries and intracranial aneurysms account for the cerebrovascular pathologies detected in C-FMD. Our understanding regarding C-FMD has been augmented in the recent past on account of dedicated C-FMD data from North American, European and other international FMD cohorts. In this review article, we provide an updated and comprehensive overview on epidemiology, clinical presentation, etiology, diagnosis and management of C-FMD.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataque Isquêmico Transitório / Displasia Fibromuscular / AVC Isquêmico Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataque Isquêmico Transitório / Displasia Fibromuscular / AVC Isquêmico Idioma: En Ano de publicação: 2023 Tipo de documento: Article