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Ertapenem plus meropenem combination treatment in carbapenem-resistant Klebsiella pneumoniae bacteremia: an analysis of 53 cases.
Önal, Ugur; Akyol, Deniz; Kaya, Arda; Baskol, Dilsah; Kenanoglu, Buse; Sanlidag, Gamze; Önal, Ayse Uyan; Avsar, Cansu Bulut; Mert, Merve; Memetali, Seichan; Erdem, Hüseyin Aytaç; Bozkurt, Devrim; Simsir, Adnan; Bozbiyik, Osman; Kahraman, Ümit; Özgiray, Erkin; Korkmaz, Pervin; Çilli, Feriha; Pullukçu, Hüsnü; Yamazhan, Tansu; Tasbakan, Meltem Isikgöz; Arda, Bilgin; Ulusoy, Sercan; Sipahi, Oguz Resat.
Afiliação
  • Önal U; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey. uguronal@uludag.edu.tr.
  • Akyol D; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey. uguronal@uludag.edu.tr.
  • Kaya A; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Baskol D; Infectious Diseases Clinic, Kagizman State Hospital, Kars, Turkey.
  • Kenanoglu B; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Sanlidag G; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Önal AU; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Avsar CB; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Mert M; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Memetali S; Yüksek Ihtisas Teaching and Research Hospital, Bursa, Turkey.
  • Erdem HA; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Bozkurt D; Çigli Teaching and Research Hospital, Bakirçay University, Izmir, Turkey.
  • Simsir A; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Bozbiyik O; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Kahraman Ü; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Özgiray E; Department of Internal Medicine, Ege University Faculty of Medicine, Izmir, Turkey.
  • Korkmaz P; Department of Urology, Ege University Faculty of Medicine, Izmir, Turkey.
  • Çilli F; Department of General Surgery, Ege University Faculty of Medicine, Izmir, Turkey.
  • Pullukçu H; Department of Cardiovascular Surgery, Ege University Faculty of Medicine, Izmir, Turkey.
  • Yamazhan T; Department of Neurosurgery, Ege University Faculty of Medicine, Izmir, Turkey.
  • Tasbakan MI; Department of Chest Diseases, Ege University Faculty of Medicine, Izmir, Turkey.
  • Arda B; Department of Medical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey.
  • Ulusoy S; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Sipahi OR; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Eur J Clin Microbiol Infect Dis ; 42(10): 1269-1273, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37676420
ABSTRACT
Herein, we aimed to describe the outcomes of patients with blood stream infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) who received ertapenem plus meropenem combination treatment (EMCT). A total of 53 patients with culture proven CR-Kp bacteremia treated with ertapenem + meropenem were included. The patients with secondary bacteremia due to urinary tract infection exhibited a significantly lower 1-month mortality (OMM), particularly in those with microbiological eradication and those with end-of-treatment success. Salvage EMCT resulted in 49% 1-month survival.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bacteriemia / Enterobacteriáceas Resistentes a Carbapenêmicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bacteriemia / Enterobacteriáceas Resistentes a Carbapenêmicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article