Development of a targeted hydrophilic interaction liquid chromatography-tandem mass spectrometry based lipidomics platform applied to a coronavirus disease severity study.

Zhang, Zhengzheng; Singh, Madhulika; Kindt, Alida; Wegrzyn, Agnieszka B; Pearson, Mackenzie J; Ali, Ahmed; Harms, Amy C; Baker, Paul; Hankemeier, Thomas

Zhang, Zhengzheng; Singh, Madhulika; Kindt, Alida; Wegrzyn, Agnieszka B; Pearson, Mackenzie J; Ali, Ahmed; Harms, Amy C; Baker, Paul; Hankemeier, Thomas.

Afiliação

Zhang Z; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands.
Singh M; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands.
Kindt A; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands.
Wegrzyn AB; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands.
Pearson MJ; SCIEX, Concord, Ontario L4K 4V8 Canada.
Ali A; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands.
Harms AC; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands.
Baker P; SCIEX, Concord, Ontario L4K 4V8 Canada.
Hankemeier T; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, the Netherlands. Electronic address: hankemeier@lacdr.leidenuniv.nl.

J Chromatogr A ; 1708: 464342, 2023 Oct 11.

Article em En | MEDLINE | ID: mdl-37696124

Assuntos

COVID-19; Lipidômica; Humanos; Espectrometria de Massas em Tandem; Pandemias; Reprodutibilidade dos Testes; Cromatografia Líquida; Gravidade do Paciente; Lipídeos

Palavras-chave

COVID-19; Clinical lipidomics; HILIC-MS/MS; NIST SRM 1950 plasma; Over-reporting; Quantitation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipidômica / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipidômica / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article