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A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models.
Ikenoshita, Susumu; Matsuo, Kazuya; Yabuki, Yasushi; Kawakubo, Kosuke; Asamitsu, Sefan; Hori, Karin; Usuki, Shingo; Hirose, Yuki; Bando, Toshikazu; Araki, Kimi; Ueda, Mitsuharu; Sugiyama, Hiroshi; Shioda, Norifumi.
Afiliação
  • Ikenoshita S; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG).
  • Matsuo K; Department of Neurology, Graduate School of Medical Sciences.
  • Yabuki Y; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG).
  • Kawakubo K; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG).
  • Asamitsu S; Graduate School of Pharmaceutical Sciences, and.
  • Hori K; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG).
  • Usuki S; Graduate School of Pharmaceutical Sciences, and.
  • Hirose Y; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG).
  • Bando T; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG).
  • Araki K; Liaison Laboratory Research Promotion Center, IMEG, Kumamoto University, Kumamoto, Japan.
  • Ueda M; Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan.
  • Sugiyama H; Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan.
  • Shioda N; Institute of Resource Development and Analysis and.
J Clin Invest ; 133(22)2023 11 15.
Article em En | MEDLINE | ID: mdl-37707954
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Distrofia Miotônica Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Distrofia Miotônica Idioma: En Ano de publicação: 2023 Tipo de documento: Article