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A Machine Learning Framework to Improve Rat Clearance Predictions and Inform Physiologically Based Pharmacokinetic Modeling.
Andrews-Morger, Andrea; Reutlinger, Michael; Parrott, Neil; Olivares-Morales, Andrés.
Afiliação
  • Andrews-Morger A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland.
  • Reutlinger M; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland.
  • Parrott N; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland.
  • Olivares-Morales A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland.
Mol Pharm ; 20(10): 5052-5065, 2023 10 02.
Article em En | MEDLINE | ID: mdl-37713584
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fígado / Modelos Biológicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fígado / Modelos Biológicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article