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Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors.
FitzGerald, Edward A; Vagrys, Darius; Opassi, Giulia; Klein, Hanna F; Hamilton, David J; Talibov, Vladimir O; Abramsson, Mia; Moberg, Anna; Lindgren, Maria T; Holmgren, Claes; Davis, Ben; O'Brien, Peter; Wijtmans, Maikel; Hubbard, Roderick E; de Esch, Iwan J P; Danielson, U Helena.
Afiliação
  • FitzGerald EA; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden; Beactica Therapeutics AB, Virdings allé 2, Uppsala, Sweden.
  • Vagrys D; Vernalis (R&D) Ltd., Granta Park, Great Abington, Cambridge, United Kingdom; YSBL, Department of Chemistry, University of York, York, United Kingdom.
  • Opassi G; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.
  • Klein HF; Department of Chemistry, University of York, York, United Kingdom.
  • Hamilton DJ; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Talibov VO; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.
  • Abramsson M; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.
  • Moberg A; Cytiva, Björkgatan 30, Uppsala, Sweden.
  • Lindgren MT; Cytiva, Björkgatan 30, Uppsala, Sweden.
  • Holmgren C; Cytiva, Björkgatan 30, Uppsala, Sweden.
  • Davis B; Vernalis (R&D) Ltd., Granta Park, Great Abington, Cambridge, United Kingdom.
  • O'Brien P; Department of Chemistry, University of York, York, United Kingdom.
  • Wijtmans M; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Hubbard RE; Vernalis (R&D) Ltd., Granta Park, Great Abington, Cambridge, United Kingdom; YSBL, Department of Chemistry, University of York, York, United Kingdom.
  • de Esch IJP; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Danielson UH; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden; Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Electronic address: helena.danielson@kemi.uu.se.
SLAS Discov ; 29(1): 40-51, 2024 Jan.
Article em En | MEDLINE | ID: mdl-37714432
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Ressonância de Plasmônio de Superfície Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Ressonância de Plasmônio de Superfície Idioma: En Ano de publicação: 2024 Tipo de documento: Article