Cohort study to assess the prevalence of prolonged QT and arrhythmias in critically ill patients during the early phase of the COVID-19 pandemic.
Rev Esp Anestesiol Reanim (Engl Ed)
; 70(10): 561-568, 2023 Dec.
Article
em En
| MEDLINE
| ID: mdl-37717632
ABSTRACT
INTRODUCTION:
Patients with SARS-CoV-2 infection may present cardiovascular involvement including myocarditis, arrhythmias and QT interval prolongation. Our objective was to evaluate the impact of COVID-19 and its treatment on ventricular repolarization and development of arrhythmias in critically ill patients.METHODS:
Retrospective cohort study of critically ill COVID-19 patients during a 3-month period in whom at least one ECG was available. Relevant clinical data and specific treatment administered for COVID-19 were recorded. Prolonged QTc was considered prolonged when it measured ≥ 460â¯ms in women and ≥450â¯ms in men. The incidence and type of arrhythmias during the same period were recorded.RESULTS:
A total of 77 patients with a mean age of 62⯱â¯13 years, 20 women and 57 men, were evaluated. Sixty percent of the patients were hypertensive, 52% had a BMI > 30, and 70% developed acute renal failure during admission. Some 56% of the patients presented QTc prolongation. Forty-four percent presented some type of arrhythmia during their stay in the ICU, 21% of which were atrial arrhythmias. Overall mortality was 53%, with no differences between patients with or without prolonged QTc.CONCLUSIONS:
In our series, a high proportion of critical patients with COVID-19 presented prolonged QTc and arrhythmias. The factors involved have been related to the elevation of cardiac biomarkers, the myocardial involvement of the virus and concomitant medication received in the ICU.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Síndrome do QT Longo
/
COVID-19
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article