Turning up the heat on essential E. coli genes.
Mol Syst Biol
; 19(10): e11933, 2023 Oct 12.
Article
em En
| MEDLINE
| ID: mdl-37718698
ABSTRACT
Temperature-sensitive (TS) alleles create tunable thermoswitches to deplete essential cellular activities and are used to dissect gene function. In their recent study, Link and colleagues (Schramm et al 2023) use a CRISPR-based approach to systematically create TS alleles across essential genes in E. coli.
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MEDLINE
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En
Ano de publicação:
2023
Tipo de documento:
Article