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Discovery of (S)-flurbiprofen-based novel azine derivatives as prostaglandin endoperoxide synthase-II inhibitors: Synthesis, in-vivo analgesic, anti-inflammatory activities, and their molecular docking.
Alam, Aftab; Ali, Mumtaz; Latif, Abdul; Ur Rehman, Najeeb; Jabbar Shah, Abdul; Amir Khan, Irfan; Ayaz, Muhammad; Ur Rahman, Sajjad; Al-Harrasi, Ahmed; Ahmad, Manzoor.
Afiliação
  • Alam A; Department of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan.
  • Ali M; Department of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan.
  • Zainab; College of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang 050024, China.
  • Latif A; Department of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan.
  • Ur Rehman N; Natural and Medical Sciences Research Center, University of Nizwa, Nizwa 616, Oman.
  • Jabbar Shah A; Cardiovascular Research Group, Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus-22060, Khyber Pakhtunkhwa, Pakistan.
  • Amir Khan I; Cardiovascular Research Group, Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus-22060, Khyber Pakhtunkhwa, Pakistan.
  • Ayaz M; Department of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan.
  • Ur Rahman S; Department of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan.
  • Al-Harrasi A; Natural and Medical Sciences Research Center, University of Nizwa, Nizwa 616, Oman. Electronic address: aharrasi@unizwa.edu.om.
  • Ahmad M; Department of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan. Electronic address: manzoorahmad@uom.edu.pk.
Bioorg Chem ; 141: 106847, 2023 12.
Article em En | MEDLINE | ID: mdl-37722268
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flurbiprofeno Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flurbiprofeno Idioma: En Ano de publicação: 2023 Tipo de documento: Article