Transcriptome profiling of patient-derived tumor xenografts suggests novel extracellular matrix-related signatures for gastric cancer prognosis prediction.

Deng, Ziqian; Guo, Ting; Bi, Jiwang; Wang, Gangjian; Hu, Ying; Du, Hong; Zhou, Yuan; Jia, Shuqin; Xing, Xiaofang; Ji, Jiafu

Deng, Ziqian; Guo, Ting; Bi, Jiwang; Wang, Gangjian; Hu, Ying; Du, Hong; Zhou, Yuan; Jia, Shuqin; Xing, Xiaofang; Ji, Jiafu.

Afiliação

Deng Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China.
Guo T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China.
Bi J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China.
Wang G; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China.
Hu Y; Biological Sample Bank, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China.
Du H; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China.
Zhou Y; Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China. zhouyuanbioinfo@hsc.pku.edu.cn.
Jia S; Department of Molecular Diagnosis, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China. shuqin_jia@hsc.pku.edu.cn.
Xing X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China. Xingxiaofang@bjmu.edu.cn.
Ji J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142, People's Republic of China. jijiafu@hsc.pku.edu.cn.

J Transl Med ; 21(1): 638, 2023 09 19.

Article em En | MEDLINE | ID: mdl-37726803

Assuntos

Neoplasias Gástricas; Humanos; Animais; Neoplasias Gástricas/genética; Xenoenxertos; Prognóstico; Carcinogênese; Perfilação da Expressão Gênica; Transformação Celular Neoplásica; Modelos Animais de Doenças; Matriz Extracelular; Microambiente Tumoral/genética

Palavras-chave

Extracellular matrix; Gastric cancer; Patient-derived tumor xenografts; Prognosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas Idioma: En Ano de publicação: 2023 Tipo de documento: Article