Removal of extracellular human amyloid beta aggregates by extracellular proteases in <i>C. elegans</i>.

Jongsma, Elisabeth; Goyala, Anita; Mateos, José Maria; Ewald, Collin Yvès

Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans.

Jongsma, Elisabeth; Goyala, Anita; Mateos, José Maria; Ewald, Collin Yvès.

Afiliação

Jongsma E; Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zürich, Schwerzenbach, Switzerland.
Goyala A; Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zürich, Schwerzenbach, Switzerland.
Mateos JM; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.
Ewald CY; Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zürich, Schwerzenbach, Switzerland.

Elife ; 122023 09 20.

Article em En | MEDLINE | ID: mdl-37728486

Assuntos

Doença de Alzheimer; Peptídeos beta-Amiloides; Animais; Humanos; Caenorhabditis elegans; Peptídeo Hidrolases; Desintegrinas; Endopeptidases; Placa Amiloide; Metaloproteases/genética; Proteínas de Membrana; Proteínas ADAM

Palavras-chave

ADAM9; Alzheimer's disease; C. elegans; TIMP; aggregation; amyloid beta; cell biology; collagen; neuroscience

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article