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NLRP3 selectively drives IL-1ß secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity.
Minns, Martin S; Liboro, Karl; Lima, Tatiane S; Abbondante, Serena; Miller, Brandon A; Marshall, Michaela E; Tran Chau, Jolynn; Roistacher, Alicia; Rietsch, Arne; Dubyak, George R; Pearlman, Eric.
Afiliação
  • Minns MS; Departments of Ophthalmology and Physiology & Biophysics, University of California, Irvine, CA, USA.
  • Liboro K; Odyssey Therapeutics, Boston, MA, USA.
  • Lima TS; Departments of Ophthalmology and Physiology & Biophysics, University of California, Irvine, CA, USA.
  • Abbondante S; Departments of Ophthalmology and Physiology & Biophysics, University of California, Irvine, CA, USA.
  • Miller BA; Department of Biological Sciences, California State Polytechnic University, Pomona, CA, USA.
  • Marshall ME; Departments of Ophthalmology and Physiology & Biophysics, University of California, Irvine, CA, USA.
  • Tran Chau J; Department of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH, USA.
  • Roistacher A; Departments of Ophthalmology and Physiology & Biophysics, University of California, Irvine, CA, USA.
  • Rietsch A; Departments of Ophthalmology and Physiology & Biophysics, University of California, Irvine, CA, USA.
  • Dubyak GR; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, USA.
  • Pearlman E; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, USA.
Nat Commun ; 14(1): 5832, 2023 09 20.
Article em En | MEDLINE | ID: mdl-37730693

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Doenças da Córnea Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Doenças da Córnea Idioma: En Ano de publicação: 2023 Tipo de documento: Article