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A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir.
Zhang, Yumin; Sun, Yuan; Xie, Yuanchao; Shang, Weijuan; Wang, Zhen; Jiang, Hualiang; Shen, Jingshan; Xiao, Gengfu; Zhang, Leike.
Afiliação
  • Zhang Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, 430071, Wuhan, China.
  • Sun Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, 430071, Wuhan, China.
  • Xie Y; University of Chinese Academy of Sciences, 100049, Beijing, China.
  • Shang W; Lingang Laboratory, 200031, Shanghai, China.
  • Wang Z; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, 430071, Wuhan, China.
  • Jiang H; Lingang Laboratory, 200031, Shanghai, China.
  • Shen J; Lingang Laboratory, 200031, Shanghai, China.
  • Xiao G; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 201203, Shanghai, China.
  • Zhang L; University of Chinese Academy of Sciences, 100049, Beijing, China. shenjingshan@simm.ac.cn.
Signal Transduct Target Ther ; 8(1): 360, 2023 09 22.
Article em En | MEDLINE | ID: mdl-37735468
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Coronavirus Humano OC43 / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Coronavirus Humano OC43 / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article