Disentangling the nonmetabolic roles of metabolites: lactate as a case study.
Trends Endocrinol Metab
; 34(12): 786-788, 2023 12.
Article
em En
| MEDLINE
| ID: mdl-37739879
Many metabolites possess covalent and noncovalent signaling functions. However, ongoing research considers them mostly as ligands, neglecting their potential involvement in post-translational modifications. In this forum article, we discuss the dual signaling functions of metabolites, using lactate as a case study, and advocate for the use of multiple complementary techniques to disentangle their functions.
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MEDLINE
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Transdução de Sinais
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Ácido Láctico
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En
Ano de publicação:
2023
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Article