Non-Invasive Biochemical Testing of ACTH-dependent Cushing's Disease: Do We Still Need Petrosal Sinus Sampling?
Arch Med Res
; 54(8): 102882, 2023 12.
Article
em En
| MEDLINE
| ID: mdl-37749028
ABSTRACT
Differentiating between a pituitary from an ectopic source of ACTH could be a real one of the major challenges of clinical endocrinology. The Bilateral inferior petrosal sinus sampling (BIPSS) is considered the gold standard for identifying the source of ACTH; however, is not available worldwide. After the SARS-CoV-2 pandemic, algorithms that include biochemical and imaging tests have gained importance as an alternative to BIPSS. This review summarizes the drawbacks in the differential diagnosis of ACTH-dependent Cushing; the evolution of diagnostic tests, and the evidence that exists on their performance. As well as a comparison between the advantages and disadvantages of invasive and non-invasive tests.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Amostragem do Seio Petroso
/
Hipersecreção Hipofisária de ACTH
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article