Your browser doesn't support javascript.
loading
Photo-induced scandium-catalyzed biomimetic skeleton conversion of lathyrane to naturally rare eupholathone Euphorbia diterpenes.
Xu, Jin-Bu; Wen, Peng; Wang, Neng; Li, Xiaohuan; Li, Jia-Hong; De Jonghe, Steven; Schols, Dominique; Chen, Feng-Zheng; Gao, Feng.
Afiliação
  • Xu JB; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, People's Republic of China. gaof@swjtu.edu.cn.
  • Wen P; Yibin Institute of Southwest Jiaotong University, Yibin 644000, Sichuan, People's Republic of China.
  • Wang N; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, People's Republic of China. gaof@swjtu.edu.cn.
  • Li X; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, People's Republic of China. gaof@swjtu.edu.cn.
  • Li JH; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, People's Republic of China. gaof@swjtu.edu.cn.
  • De Jonghe S; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, People's Republic of China. gaof@swjtu.edu.cn.
  • Schols D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, box 1043, Leuven 3000, Belgium.
  • Chen FZ; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, box 1043, Leuven 3000, Belgium.
  • Gao F; College of Chemistry, Leshan Normal University, Leshan 614004, Sichuan, People's Republic of China. fzchen7200@163.com.
Chem Commun (Camb) ; 59(82): 12290-12293, 2023 Oct 12.
Article em En | MEDLINE | ID: mdl-37752884
ABSTRACT
The naturally scarce eupholathone-type euphornin E (1) was efficiently prepared from abundant lathyrane-type Euphorbia factor L1via a visible-light-induced Sc(OTf)3-catalyzed tandem process. Eupholathones 2 and 3 were also smoothly obtained by changing the reaction solvent. This route provides a convenient method for easily constructing scarce eupholathone- from lathyrane-type Euphorbia diterpenes, and confirms the biogenetic relationship between them from a chemical standpoint. Notably, compound 1 exhibited good anti-HIV activity.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Euphorbia / Diterpenos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Euphorbia / Diterpenos Idioma: En Ano de publicação: 2023 Tipo de documento: Article