Licochalcone A induces G2/M phase arrest and apoptosis via regulating p53 pathways in esophageal cancer: In-vitro and in-vivo study.

Liu, Jia; Deng, Liangyan; Wang, Lingyu; Qian, Die; He, Chengxun; Ren, Qiang; Zhang, Qing; Chen, Yunhui

Liu, Jia; Deng, Liangyan; Wang, Lingyu; Qian, Die; He, Chengxun; Ren, Qiang; Zhang, Qing; Chen, Yunhui.

Afiliação

Liu J; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China.
Deng L; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China.
Wang L; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China.
Qian D; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China.
He C; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China.
Ren Q; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, PR China. Electronic address: 401627406@qq.com.
Zhang Q; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China. Electronic address: zhangqcdutcm@163.com.
Chen Y; Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China. Electronic address: chenyunhui@cdutcm.edu.cn.

Eur J Pharmacol ; 958: 176080, 2023 Nov 05.

Article em En | MEDLINE | ID: mdl-37758012

Assuntos

Neoplasias Esofágicas; Proteína Supressora de Tumor p53; Humanos; Proteína Supressora de Tumor p53/metabolismo; Simulação de Acoplamento Molecular; Apoptose; Proliferação de Células; Mitose; Neoplasias Esofágicas/tratamento farmacológico; Linhagem Celular Tumoral

Palavras-chave

Apoptosis; Cell cycle arrest; Esophagus cancer; Licochalcone A; p53

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Proteína Supressora de Tumor p53 Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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