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ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes.
Lee, Hyein; Cho, Sukhee; Kim, Mi-Jin; Park, Yeo Jin; Cho, Eunji; Jo, Yeon Suk; Kim, Yong-Seok; Lee, Jung Yi; Thoudam, Themis; Woo, Seung-Hwa; Lee, Se-In; Jeon, Juyeong; Lee, Young-Sam; Suh, Byung-Chang; Yoon, Jong Hyuk; Go, Younghoon; Lee, In-Kyu; Seo, Jinsoo.
Afiliação
  • Lee H; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Cho S; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Kim MJ; Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 41944, South Korea.
  • Park YJ; Korean Medicine Life Science, University of Science and Technology, Daejeon 34054, South Korea; Korean Medicine-Application Center, Korea Institute of Oriental Medicine, Daegu 41062, South Korea.
  • Cho E; Neurodegenerative Disease Research Group, Korea Brain Research Institute, Daegu 41062, South Korea.
  • Jo YS; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea; Neurodegenerative Disease Research Group, Korea Brain Research Institute, Daegu 41062, South Korea.
  • Kim YS; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Lee JY; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University School of Medicine, Daegu 41944, South Korea.
  • Thoudam T; Research Institute of Aging and Metabolism, Kyungpook National University School of Medicine, Daegu 41944, South Korea.
  • Woo SH; Department of New Biology, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Lee SI; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Jeon J; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Lee YS; Department of New Biology, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Suh BC; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea.
  • Yoon JH; Neurodegenerative Disease Research Group, Korea Brain Research Institute, Daegu 41062, South Korea.
  • Go Y; Korean Medicine-Application Center, Korea Institute of Oriental Medicine, Daegu 41062, South Korea. Electronic address: gotra827@kiom.re.kr.
  • Lee IK; Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 41944, South Korea; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University School of Medicine, Daegu 41944, South Korea; Research Instit
  • Seo J; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu 42988, South Korea. Electronic address: jsseo@dgist.ac.kr.
Cell Rep ; 42(10): 113183, 2023 10 31.
Article em En | MEDLINE | ID: mdl-37777962
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article