An integrated nationwide genomics study reveals transmission modes of typhoid fever in China.
mBio
; 14(5): e0133323, 2023 Oct 31.
Article
em En
| MEDLINE
| ID: mdl-37800953
ABSTRACT
IMPORTANCE Typhoid fever is a life-threatening disease caused by Salmonella enterica serovar Typhi, resulting in a significant disease burden across developing countries. Historically, China was very much close to the global epicenter of typhoid, but the role of typhoid transmission within China and among epicenter remains overlooked in previous investigations. By using newly produced genomics on a national scale, we clarify the complex local and global transmission history of such a notorious disease agent in China spanning the most recent five decades, which largely undermines the global public health network.
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Base de dados:
MEDLINE
Assunto principal:
Febre Tifoide
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article