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An integrated nationwide genomics study reveals transmission modes of typhoid fever in China.
Feng, Ye; Pan, Hang; Zheng, Beiwen; Li, Fang; Teng, Lin; Jiang, Zhijie; Feng, Mengyao; Zhou, Xiao; Peng, Xianqi; Xu, Xuebin; Wang, Haoqiu; Wu, Beibei; Xiao, Yonghong; Baker, Stephen; Zhao, Guoping; Yue, Min.
Afiliação
  • Feng Y; Sir Run Run Shaw Hospital, Zhejiang University School of Medicine , Hangzhou, China.
  • Pan H; Institute of Translational Medicine, Zhejiang University School of Medicine , Hangzhou, China.
  • Zheng B; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Li F; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, China.
  • Teng L; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Jiang Z; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Feng M; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Zhou X; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Peng X; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Xu X; Department of Veterinary Medicine, Zhejiang University College of Animal Sciences , Hangzhou, China.
  • Wang H; Shanghai Municipal Center for Disease Control and Prevention , Shanghai, China.
  • Wu B; Hangzhou Center for Disease Control and Prevention , Hangzhou, China.
  • Xiao Y; Zhejiang Province Center for Disease Control and Prevention , Hangzhou, China.
  • Baker S; School of Public Health and Managemet, Wenzhou Medical University , Wenzhou, Zhejiang, China.
  • Zhao G; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, China.
  • Yue M; University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus , Cambridge, United Kingdom.
mBio ; 14(5): e0133323, 2023 Oct 31.
Article em En | MEDLINE | ID: mdl-37800953
ABSTRACT
IMPORTANCE Typhoid fever is a life-threatening disease caused by Salmonella enterica serovar Typhi, resulting in a significant disease burden across developing countries. Historically, China was very much close to the global epicenter of typhoid, but the role of typhoid transmission within China and among epicenter remains overlooked in previous investigations. By using newly produced genomics on a national scale, we clarify the complex local and global transmission history of such a notorious disease agent in China spanning the most recent five decades, which largely undermines the global public health network.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Febre Tifoide Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Febre Tifoide Idioma: En Ano de publicação: 2023 Tipo de documento: Article