CDDO-Me ameliorates podocyte injury through anti-oxidative stress and regulation of actin cytoskeleton in adriamycin nephropathy.

Xu, Cheng; Liu, Xing; Zhai, Xiuwen; Wang, Gang; Qin, Weisong; Cheng, Zheng; Chen, Zhaohong

Xu, Cheng; Liu, Xing; Zhai, Xiuwen; Wang, Gang; Qin, Weisong; Cheng, Zheng; Chen, Zhaohong.

Afiliação

Xu C; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China; Department of Nephrology, The Second Hospital of Jilin University, Nanguan District, Changchun 130041, Jilin, China.
Liu X; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Zhai X; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Wang G; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Qin W; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Cheng Z; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China. Electronic address: chengzhen33@hotmail.com.
Chen Z; National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China. Electronic address: chenzhaohong@nju.edu.cn.

Biomed Pharmacother ; 167: 115617, 2023 Nov.

Article em En | MEDLINE | ID: mdl-37801905

Assuntos

Glomerulosclerose Segmentar e Focal; Nefropatias; Podócitos; Camundongos; Animais; Glomerulosclerose Segmentar e Focal/induzido quimicamente; Glomerulosclerose Segmentar e Focal/tratamento farmacológico; Doxorrubicina/farmacologia; Fator 2 Relacionado a NF-E2/metabolismo; Nefropatias/induzido quimicamente; Nefropatias/tratamento farmacológico; Nefropatias/metabolismo; Citoesqueleto de Actina/metabolismo; Estresse Oxidativo; Inflamação/metabolismo

Palavras-chave

Focal segmental glomerulosclerosis; NRF2; Podocyte injury

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glomerulosclerose Segmentar e Focal / Podócitos / Nefropatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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