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Structural and solution speciation studies on selected [Cu(NN)(OO)] complexes and an investigation of their biomimetic activity, ROS generation and their cytotoxicity in normoxic, hypoxic and anoxic environments in MCF-7 breast cancer-derived cells.
Jenkins, Hollie; MacLean, Louise; McClean, Siobhán; Cooke, Gordon; Devereux, Michael; Howe, Orla; Pereira, Marcos D; May, Nóra V; Enyedy, Éva A; Creaven, Bernadette S.
Afiliação
  • Jenkins H; Centre of Applied Science for Health, TU Dublin, Tallaght Campus, D24 FKT9, Ireland.
  • MacLean L; Centre of Applied Science for Health, TU Dublin, Tallaght Campus, D24 FKT9, Ireland.
  • McClean S; School of Biomolecular and Biomedical Science, University College Dublin, Belfield Dublin 4, Ireland.
  • Cooke G; Centre of Applied Science for Health, TU Dublin, Tallaght Campus, D24 FKT9, Ireland; School of Chemical and BioPharmaceutical Sciences, Technological University Dublin, Central Quad Building, Grangegorman, Dublin D07 ADY7, Ireland.
  • Devereux M; Centre for Biomimetic and Therapeutic Research, Focas Research Institute, TU Dublin, Camden Row, Dublin 8, Ireland.
  • Howe O; Centre for Biomimetic and Therapeutic Research, Focas Research Institute, TU Dublin, Camden Row, Dublin 8, Ireland; School of Biological, Health and Sport Sciences, TU Dublin, City Campus, D07 XT95, Ireland.
  • Pereira MD; Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Brazil; Rede de Micrologia - FAPERJ, Rio de Janeiro, Brazil.
  • May NV; Centre for Structural Sciences, Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest H-1117, Hungary.
  • Enyedy ÉA; Departmen of Molecular and Analytical Chemistry, Interdisciplinary Excellence Centre and MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, Szeged H-6720, Hungary.
  • Creaven BS; Centre of Applied Science for Health, TU Dublin, Tallaght Campus, D24 FKT9, Ireland; School of Chemical and BioPharmaceutical Sciences, Technological University Dublin, Central Quad Building, Grangegorman, Dublin D07 ADY7, Ireland. Electronic address: bernie.creaven@tudublin.ie.
J Inorg Biochem ; 249: 112383, 2023 12.
Article em En | MEDLINE | ID: mdl-37804698
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Complexos de Coordenação / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Complexos de Coordenação / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article