Electrochemical Oxidative Carbonylation of NH-Sulfoximines.
Org Lett
; 25(41): 7529-7534, 2023 Oct 20.
Article
em En
| MEDLINE
| ID: mdl-37819202
ABSTRACT
The electrochemical synthesis of N-aroylsulfoximines features the use of tetra-n-butylammonium iodide (TBAI) as the medium and a broad substrate scope, thus affording a wide range of N-aroylated sulfoximines in moderate to good yields. The advantages of this electrochemical strategy are augmented by mild reaction conditions that are external oxidant-free, ligand-free, and easy to scale up to gram scale. Both the control experiments and the mechanistic studies revealed that the whole electrochemical process proceeded through a palladium (II/IV/II) catalytic cycle.
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MEDLINE
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En
Ano de publicação:
2023
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Article