MiR-148a-3p within HucMSC-Derived Extracellular Vesicles Suppresses Hsp90b1 to Prevent Fibroblast Collagen Synthesis and Secretion in Silica-Induced Pulmonary Fibrosis.

Jiang, Qiyue; Zhao, Jing; Jia, Qiyue; Wang, Hongwei; Xue, Wenming; Ning, Fuao; Wang, Jiaxin; Wang, Yan; Zhu, Zhonghui; Tian, Lin

Jiang, Qiyue; Zhao, Jing; Jia, Qiyue; Wang, Hongwei; Xue, Wenming; Ning, Fuao; Wang, Jiaxin; Wang, Yan; Zhu, Zhonghui; Tian, Lin.

Afiliação

Jiang Q; Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China.
Zhao J; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.
Jia Q; Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China.
Wang H; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.
Xue W; Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China.
Ning F; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.
Wang J; Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China.
Wang Y; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.
Zhu Z; Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China.
Tian L; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Int J Mol Sci ; 24(19)2023 Sep 23.

Article em En | MEDLINE | ID: mdl-37833927

Assuntos

Vesículas Extracelulares; MicroRNAs; Fibrose Pulmonar; Silicose; Humanos; Fibrose Pulmonar/induzido quimicamente; Fibrose Pulmonar/genética; Fibrose Pulmonar/terapia; Fator de Crescimento Transformador beta1/metabolismo; Dióxido de Silício/farmacologia; MicroRNAs/metabolismo; Silicose/genética; Silicose/terapia; Silicose/patologia; Fibroblastos/metabolismo; Colágeno/farmacologia; Vesículas Extracelulares/metabolismo

Palavras-chave

Hsp90b1; HucMSCs; MiR-148a-3p; extracellular vesicles; fibroblasts; pulmonary fibrosis; silica

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Silicose / MicroRNAs / Vesículas Extracelulares Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google