Synthesis, molecular modeling investigation, molecular dynamic and ADME prediction of some novel Mannich bases derived from 1,2,4-triazole, and assessment of their anticancer activity.

Manap, Sevda; Medetalibeyoglu, Hilal; Kiliç, Ahsen; Karatas, Omer Faruk; Tüzün, Burak; Alkan, Muzaffer; Ortaakarsu, Ahmet Bugra; Atalay, Abdurrahman; Beytur, Murat; Yüksek, Haydar

Manap, Sevda; Medetalibeyoglu, Hilal; Kiliç, Ahsen; Karatas, Omer Faruk; Tüzün, Burak; Alkan, Muzaffer; Ortaakarsu, Ahmet Bugra; Atalay, Abdurrahman; Beytur, Murat; Yüksek, Haydar.

Afiliação

Manap S; Department of Chemistry, Kafkas University, Kars, Turkey.
Medetalibeyoglu H; Department of Chemistry, Kafkas University, Kars, Turkey.
Kiliç A; Molecular Biology and Genetics Department, Erzurum Technical University, Erzurum, Turkey.
Karatas OF; High Technology Application and Research Center, Erzurum Technical University, Erzurum, Turkey.
Tüzün B; Molecular Biology and Genetics Department, Erzurum Technical University, Erzurum, Turkey.
Alkan M; High Technology Application and Research Center, Erzurum Technical University, Erzurum, Turkey.
Ortaakarsu AB; Plant and Animal Production Department, Sivas Technical Sciences Vocational School, Sivas Cumhuriyet University, Turkey.
Atalay A; Education Faculty, Kafkas University, Kars, Turkey.
Beytur M; Department of Chemistry, Gazi University, Ankara, Turkey.
Yüksek H; Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.