The Impact of Microgravity on Immunological States.
Immunohorizons
; 7(10): 670-682, 2023 10 01.
Article
em En
| MEDLINE
| ID: mdl-37855736
ABSTRACT
As we explore other planetary bodies, astronauts will face unique environmental and physiological challenges. The human immune system has evolved under Earth's gravitational force. Consequently, in the microgravity environment of space, immune function is altered. This can pose problematic consequences for astronauts on deep space missions where medical intervention will be limited. Studying the unique environment of microgravity has its challenges, yet current research has uncovered immunological states that are probable during exploration missions. As microgravity-induced immune states are uncovered, novel countermeasure developments and personalized mitigation programs can be designed to improve astronaut health. This can also benefit immune-related monitoring programs for disorders on Earth. This is a comprehensive review, including gaps in knowledge, of simulated and spaceflight microgravity studies in human and rodent models.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Voo Espacial
/
Ausência de Peso
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article