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ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial.
Rossios, Christos; Bashir, Tufail; Achison, Marcus; Adamson, Simon; Akpan, Asangaedem; Aspray, Terry; Avenell, Alison; Band, Margaret M; Burton, Louise A; Cvoro, Vera; Donnan, Peter T; Duncan, Gordon W; George, Jacob; Gordon, Adam L; Gregson, Celia L; Hapca, Adrian; Hume, Cheryl; Jackson, Thomas A; Kerr, Simon; Kilgour, Alixe; Masud, Tahir; McKenzie, Andrew; McKenzie, Emma; Patel, Harnish; Pilvinyte, Kristina; Roberts, Helen C; Sayer, Avan A; Smith, Karen T; Soiza, Roy L; Steves, Claire J; Struthers, Allan D; Tiwari, Divya; Whitney, Julie; Witham, Miles D; Kemp, Paul R.
Afiliação
  • Rossios C; Cardiovascular and Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom.
  • Bashir T; Cardiovascular and Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom.
  • Achison M; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Adamson S; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Akpan A; University of Liverpool, Liverpool University Hospitals NHS FT Trust, Clinical Research Network Northwest Coast, Liverpool, United Kingdom.
  • Aspray T; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Translational Clinical Research Institute, Newcastle University, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.
  • Avenell A; Health Services Research Unit, University of Aberdeen, Aberdeen, United Kingdom.
  • Band MM; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Burton LA; Medicine for the Elderly, NHS Tayside, Dundee, United Kingdom.
  • Cvoro V; Ageing and Health, University of Dundee, Dundee, United Kingdom.
  • Donnan PT; Victoria Hospital, Kirkcaldy, United Kingdom.
  • Duncan GW; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
  • George J; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
  • Gordon AL; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
  • Gregson CL; Medicine for the Elderly, NHS Lothian, Edinburgh, United Kingdom.
  • Hapca A; Dept Clinical Pharmacology, Division of Molecular & Clinical Medicine, University of Dundee Medical School, Ninewells Hospital, Dundee, United Kingdom.
  • Hume C; Unit of Injury, Inflammation and Recovery, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
  • Jackson TA; NIHR Nottingham Biomedical Research Centre, Department of Medicine for the Elderly, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom.
  • Kerr S; Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Kilgour A; Older Person's Unit, Royal United Hospital NHS Foundation Trust Bath, Bath, United Kingdom.
  • Masud T; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • McKenzie A; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • McKenzie E; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom.
  • Patel H; Department of Older People's Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
  • Pilvinyte K; Medicine for the Elderly, NHS Lothian, Edinburgh, United Kingdom.
  • Roberts HC; Ageing and Health Research Group, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
  • Sayer AA; Clinical Gerontology Research Unit, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, United Kingdom.
  • Smith KT; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Soiza RL; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Steves CJ; NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHSFT, Southampton, Hampshire, United Kingdom.
  • Struthers AD; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Tiwari D; Academic Geriatric Medicine, University of Southampton, Mailpoint 807 Southampton General Hospital, Southampton, United Kingdom.
  • Whitney J; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Translational Clinical Research Institute, Newcastle University, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.
  • Witham MD; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom.
  • Kemp PR; Ageing & Clinical Experimental Research (ACER) Group, University of Aberdeen, Aberdeen, United Kingdom.
PLoS One ; 18(10): e0292402, 2023.
Article em En | MEDLINE | ID: mdl-37862321
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcopenia Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcopenia Idioma: En Ano de publicação: 2023 Tipo de documento: Article