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Discovery of novel amidobenzimidazole derivatives as orally available small molecule modulators of stimulator of interferon genes for cancer immunotherapy.
Jeon, Min Jae; Lee, Hyelim; Jo, Seongman; Kang, Miso; Jeong, Jeong Hyun; Jeong, So Hyeon; Lee, Joo-Youn; Song, Gyu Yong; Choo, Hyunah; Lee, Sanghee; Kim, Hyejin.
Afiliação
  • Jeon MJ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
  • Lee H; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
  • Jo S; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea; Department of Pharmacy, College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea.
  • Kang M; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea; Department of Basic Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, 02447, Republic of Korea.
  • Jeong JH; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
  • Jeong SH; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea; Department of Pharmacy, College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea.
  • Lee JY; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
  • Song GY; Department of Pharmacy, College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea.
  • Choo H; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
  • Lee S; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea; Department for HY-KIST Bio-convergence, Hanyang University, Seoul, 04763, Republic of Korea. Electronic address: slee19@kist.re.kr.
  • Kim H; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea. Electronic address: hjinkim@krict.re.kr.
Eur J Med Chem ; 261: 115834, 2023 Dec 05.
Article em En | MEDLINE | ID: mdl-37862818

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunidade Inata / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunidade Inata / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article