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Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson's disease-linked LRRK2 kinase.
Dhekne, Herschel S; Tonelli, Francesca; Yeshaw, Wondwossen M; Chiang, Claire Y; Limouse, Charles; Jaimon, Ebsy; Purlyte, Elena; Alessi, Dario R; Pfeffer, Suzanne R.
Afiliação
  • Dhekne HS; Department of Biochemistry, Stanford University School of Medicine, Stanford, United States.
  • Tonelli F; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Stanford, United States.
  • Yeshaw WM; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Stanford, United States.
  • Chiang CY; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, United Kingdom.
  • Limouse C; Department of Biochemistry, Stanford University School of Medicine, Stanford, United States.
  • Jaimon E; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Stanford, United States.
  • Purlyte E; Department of Biochemistry, Stanford University School of Medicine, Stanford, United States.
  • Alessi DR; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Stanford, United States.
  • Pfeffer SR; Department of Biochemistry, Stanford University School of Medicine, Stanford, United States.
Elife ; 122023 Oct 24.
Article em En | MEDLINE | ID: mdl-37874635
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas rab de Ligação ao GTP / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas rab de Ligação ao GTP / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Idioma: En Ano de publicação: 2023 Tipo de documento: Article