Functional annotation with expression validation identifies novel metastasis-relevant genes from post-GWAS risk loci in sporadic colorectal carcinomas.

Thean, Lai Fun; Wong, Michelle; Lo, Michelle; Tan, Iain; Wong, Evelyn; Gao, Fei; Tan, Emile; Tang, Choong Leong; Cheah, Peh Yean

Thean, Lai Fun; Wong, Michelle; Lo, Michelle; Tan, Iain; Wong, Evelyn; Gao, Fei; Tan, Emile; Tang, Choong Leong; Cheah, Peh Yean.

Afiliação

Thean LF; Department of Colorectal Surgery, Singapore General Hospital, Singapore.
Wong M; Department of Colorectal Surgery, Singapore General Hospital, Singapore.
Lo M; Department of Colorectal Surgery, Singapore General Hospital, Singapore.
Tan I; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Wong E; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Gao F; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.
Tan E; Duke-NUS Medical School, National University of Singapore, Singapore.
Tang CL; Department of Colorectal Surgery, Singapore General Hospital, Singapore.
Cheah PY; Department of Colorectal Surgery, Singapore General Hospital, Singapore.

J Med Genet ; 61(3): 276-283, 2024 Feb 21.

Article em En | MEDLINE | ID: mdl-37890997

Assuntos

Neoplasias Colorretais; Estudo de Associação Genômica Ampla; Humanos; Predisposição Genética para Doença; Neoplasias Colorretais/genética; Neoplasias Colorretais/patologia; Genes Neoplásicos; Polimorfismo de Nucleotídeo Único/genética; Proteínas Adaptadoras de Transdução de Sinal/genética

Palavras-chave

Gastroenterology; Gene Expression; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Estudo de Associação Genômica Ampla Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google