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N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.
Varland, Sylvia; Silva, Rui Duarte; Kjosås, Ine; Faustino, Alexandra; Bogaert, Annelies; Billmann, Maximilian; Boukhatmi, Hadi; Kellen, Barbara; Costanzo, Michael; Drazic, Adrian; Osberg, Camilla; Chan, Katherine; Zhang, Xiang; Tong, Amy Hin Yan; Andreazza, Simonetta; Lee, Juliette J; Nedyalkova, Lyudmila; Usaj, Matej; Whitworth, Alexander J; Andrews, Brenda J; Moffat, Jason; Myers, Chad L; Gevaert, Kris; Boone, Charles; Martinho, Rui Gonçalo; Arnesen, Thomas.
Afiliação
  • Varland S; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway. sylvia.varland@gmail.com.
  • Silva RD; Department of Biological Sciences, University of Bergen, N-5006, Bergen, Norway. sylvia.varland@gmail.com.
  • Kjosås I; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada. sylvia.varland@gmail.com.
  • Faustino A; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal. rfdsilva@gmail.com.
  • Bogaert A; Faculdade de Medicina e Ciências Biomédicas, Universidade do Algarve, 8005-139, Faro, Portugal. rfdsilva@gmail.com.
  • Billmann M; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway.
  • Boukhatmi H; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal.
  • Kellen B; VIB-UGent Center for Medical Biotechnology, B-9052, Ghent, Belgium.
  • Costanzo M; Department of Biomolecular Medicine, Ghent University, B-9052, Ghent, Belgium.
  • Drazic A; Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
  • Osberg C; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, D-53127, Bonn, Germany.
  • Chan K; Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes 1, CNRS, UMR6290, 35065, Rennes, France.
  • Zhang X; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal.
  • Tong AHY; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Andreazza S; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway.
  • Lee JJ; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway.
  • Nedyalkova L; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Usaj M; Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
  • Whitworth AJ; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Andrews BJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Moffat J; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Myers CL; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Gevaert K; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Boone C; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Martinho RG; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Arnesen T; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 3E1, Canada.
Nat Commun ; 14(1): 6774, 2023 10 27.
Article em En | MEDLINE | ID: mdl-37891180

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Longevidade Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Longevidade Idioma: En Ano de publicação: 2023 Tipo de documento: Article