Genomic analysis of penicillin-binding proteins and recombination events in an emerging amoxicillin- and meropenem-resistant PMEN3 (Spain<sup>9V</sup>-3, ST156) variant in Taiwan and comparison with global descendants of this lineage.

Chen, Yi-Yin; Chi, Hsin; Liao, Wei-Chao; Li, Shiao-Wen; Yang, Yu-Ching; Lin, Ho-Chen; Chang, Hsiao-Pei; Pan, Yi-Jiun; Chiang, Ruei-Lin; Hsieh, Yu-Chia

Genomic analysis of penicillin-binding proteins and recombination events in an emerging amoxicillin- and meropenem-resistant PMEN3 (Spain^9V-3, ST156) variant in Taiwan and comparison with global descendants of this lineage.

Chen, Yi-Yin; Chi, Hsin; Liao, Wei-Chao; Li, Shiao-Wen; Yang, Yu-Ching; Lin, Ho-Chen; Chang, Hsiao-Pei; Pan, Yi-Jiun; Chiang, Ruei-Lin; Hsieh, Yu-Chia.

Afiliação

Chen Y-Y; Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine , Taoyuan, Taiwan.
Chi H; Department of Medicine, MacKay Medicine College , New Taipei, Taiwan.
Liao W-C; Department of Pediatrics, MacKay Children's Hospital and MacKay Memorial Hospital , Taipei, Taiwan.
Li S-W; Department of Medical Research, MacKay Memorial Hospital , Taipei, Taiwan.
Yang Y-C; Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine , Taoyuan, Taiwan.
Lin H-C; Molecular Medicine Research Center, Chang Gung University , Taoyuan, Taiwan.
Chang H-P; Molecular Medicine Research Center, Chang Gung University , Taoyuan, Taiwan.
Pan Y-J; Department of Life Sciences, National University of Kaohsiung , Kaohsiung, Taiwan.
Chiang R-L; Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine , Taoyuan, Taiwan.
Hsieh Y-C; Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine , Taoyuan, Taiwan.

Microbiol Spectr ; 11(6): e0184023, 2023 Dec 12.

Article em En | MEDLINE | ID: mdl-37930013

Assuntos

Amoxicilina; Infecções Pneumocócicas; Humanos; Amoxicilina/farmacologia; Proteínas de Ligação às Penicilinas/genética; Proteínas de Ligação às Penicilinas/metabolismo; Meropeném; Espanha/epidemiologia; Ceftriaxona; Taiwan/epidemiologia; Vacinas Conjugadas/metabolismo; Streptococcus pneumoniae; Infecções Pneumocócicas/epidemiologia; Sorogrupo; beta-Lactamas; Testes de Sensibilidade Microbiana; Genômica; Recombinação Genética; Polissacarídeos/metabolismo

Palavras-chave

PMEN3 variant; Streptococcus pneumoniae; antibiotic resistant; clonal shift; non-vaccine serotype; ß-lactam resistant

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Amoxicilina Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Amoxicilina Idioma: En Ano de publicação: 2023 Tipo de documento: Article