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A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a nonhemophilic state.
Teranishi-Ikawa, Yuri; Soeda, Tetsuhiro; Koga, Hikaru; Yamaguchi, Kazuki; Kato, Kazuki; Esaki, Keiko; Asanuma, Kentaro; Funaki, Miho; Ichiki, Mina; Ikuta, Yuri; Ito, Shunsuke; Joyashiki, Eri; Komatsu, Shun-Ichiro; Muto, Atsushi; Nishimura, Kei; Okuda, Momoko; Sanada, Hisakazu; Sato, Motohiko; Shibahara, Norihito; Wakabayashi, Tetsuya; Yamaguchi, Koji; Matsusaki, Akiko; Sampei, Zenjiro; Shiraiwa, Hirotake; Konishi, Hiroko; Kawabe, Yoshiki; Hattori, Kunihiro; Kitazawa, Takehisa; Igawa, Tomoyuki.
Afiliação
  • Teranishi-Ikawa Y; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Soeda T; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Koga H; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan. Electronic address: koga.hikaru78@chugai-pharm.co.jp.
  • Yamaguchi K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Kato K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Esaki K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Asanuma K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Funaki M; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Ichiki M; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Ikuta Y; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Ito S; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Joyashiki E; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Komatsu SI; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Muto A; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Nishimura K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Okuda M; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Sanada H; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Sato M; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Shibahara N; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Wakabayashi T; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Yamaguchi K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Matsusaki A; Translational Research Division, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan.
  • Sampei Z; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Shiraiwa H; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Konishi H; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Kawabe Y; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Hattori K; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Kitazawa T; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan.
  • Igawa T; Research Division, Chugai Pharmaceutical Co, Ltd, Yokohama, Kanagawa, Japan; Translational Research Division, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan.
J Thromb Haemost ; 22(2): 430-440, 2024 Feb.
Article em En | MEDLINE | ID: mdl-37940048
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemostáticos / Anticorpos Biespecíficos / Hemofilia A Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemostáticos / Anticorpos Biespecíficos / Hemofilia A Idioma: En Ano de publicação: 2024 Tipo de documento: Article